2005 Feb 10
Two Waterloo projects claimed second and third place in the Sixth Critical Assessment of Techniques for Protein Structure Prediction (CASP6). Waterloo's ACE server placed second in the meta-server category, and the RAPTOR server placed third in the individual-server category.
Two years ago, RAPTOR was ranked first in CAFASP3, which ran in parallel with CASP5.
The biennial CASP represents the Olympic Games of the protein structure prediction world. CASP6 ran from May 2004 until August 2004. More than 60 prediction servers and more than 200 human expert groups worldwide registered for the event, where competitors attempt to predict the 3D structure of a protein from a description of its contents at a molecular level.
The results were released at the December 2004 CASP6 meeting. ACE ranked second behind the ROBETTA server. Due to the suprising performance of ACE, the UW research group was selected by the CASP6 organizers for the first time in CASP meetings to give a server group talk, at the CASP6 conference. The research group comprises Libo Yu, a Master's student at Waterloo, Dr. Jinbo Xu, now at MIT, and Professor Ming Li, CRC Chair in Bioinformatics at School of Computer Science, Waterloo. The work was done in collaboration with Professor Brendan McConkey's group at Waterloo's Department of Biology, and it was supported by Waterloo's supercomputer Flexor and the Bioinformatics group's cluster Genome.

David R. Cheriton School of Computer Science
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